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Sega Top Five (Brazil)
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Sega Sports 1 (Europe)
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Second Samurai (Europe)
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SeaQuest DSV (USA)
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SeaQuest DSV (Europe)
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SD Valis (Japan)
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Scrabble (Europe) (Proto)
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Scourge in Sonic 3
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Scooby Doo Mystery (USA)
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Saturday Night Slammasters (USA)
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Saturday Night Slammasters (Europe)
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SatAM Sonic in Sonic 3 & Knuckles
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Sanguozhi V (China) (Unl)
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Sanguozhi Liezhuan - Luanshi Qunying (China)
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Sangokushi Retsuden - Ransei no Eiyuutachi (Japan)
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Sangokushi III (Japan)
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Sangokushi II (Japan)
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Samurai Spirits (Japan)
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Samurai Shodown (USA)
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Samurai Shodown (Europe)
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Sampras Tennis 96 (Europe) (J-Cart)
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Same! Same! Same! (Japan)
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Sally Acorn in Sonic the Hedgehog
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Saint Sword (USA)
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Saint Sword (Japan)
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Sagaia (USA)
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S1Fixed Beta
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S1 Physics in Sonic 2
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S Factor Sonia and Silver, The by Aquaslash (V0.5)
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Ryuuko no Ken (Japan)